(Chloromethylene)dimethyliminium chloride

• Catalog No.: 25130
• CAS Number: 3724-43-4
• M. F.: C3H7Cl2N
• M. W.: 128.00038
• Purity: ≥97.0% (AT)

SYNONYMS

• Title: (氯亚甲基)二甲基氯化铵
• IUPAC name: (chloromethylidene)dimethylazanium chloride
• IUPAC Traditional name: (chloromethylidene)dimethylazanium chloride
• Synonyms: 维尔斯梅尔试剂; Dimethylchloroformiminium chloride; (Chlormethylene)dimethylammonium chloride; Arnold′s reagent; Vilsmeier reagent; 氯甲叉二甲基氯化铵

DATABASE IDS

• Beilstein Number: 3566322
• MDL Number: MFCD00011868
• CAS Number: 3724-43-4
• PubChem SID: 24855124
• EC Number: 425-970-6

PROPERTIES

• Grade: purum
• Linear Formula: ClCH=N(CH3)2Cl
• Purity: ≥97.0% (AT)
• Melting Point: 132 °C (dec.)(lit.)
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H314-H360D
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P280-P305 + P351 + P338-P310
• RID/ADR: UN 3261 8/PG 2
• Risk Statements: 61-14-22-35
• Safety Statements: 53-26-36/37/39-45
• Storage Temperature: 2-8°C
• Supplemental Hazard Statements: Reacts violently with water.
• Hazard Class: 8
• UN Number: 3261
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Reagent for preparing heterocycles9; For aromatic formylations10
Application
Reagent or Reactant for the synthesis of:
• β-Lactams vis the Staudinger reaction1
• N-vinyl substituted indoles via cross coupling of NH-indoles with vinyl bromides2
• Multi ring-fused 2-pyridone-based fluorescent scaffold3
• ester prodrugs as anti-poxvirus agents4
• Trimethine cyanine dyes for sensing G-quadruplex formation5
• Phospha-isosteres via Hundsdiecker-Barton iododecacarboxylation6
• 2-Azetidinones via [2+2]-cycloaddition7Used for studying organic photosensitizers for application in dye-sensitized solar cells8

Description (简体中文)

Other Notes
制备杂环化合物9的试剂；用于芳香烃的甲酰化10
Application
Reagent or Reactant for the synthesis of:
• β-Lactams vis the Staudinger reaction1
• N-vinyl substituted indoles via cross coupling of NH-indoles with vinyl bromides2
• Multi ring-fused 2-pyridone-based fluorescent scaffold3
• ester prodrugs as anti-poxvirus agents4
• Trimethine cyanine dyes for sensing G-quadruplex formation5
• Phospha-isosteres via Hundsdiecker-Barton iododecacarboxylation6
• 2-Azetidinones via [2+2]-cycloaddition7Used for studying organic photosensitizers for application in dye-sensitized solar cells8