Paromomycin sulfate salt

• Catalog No.: 76261
• CAS Number: 1263-89-4
• M. F.: C23H47N5O18S
• M. W.: 713.70698
• Purity: >98.0% (TLC)

SYNONYMS

• Title: Paromomycin sulfate salt 硫酸盐
• IUPAC name: (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol; sulfuric acid
• IUPAC Traditional name: (2R,3S,4R,5R,6S)-5-amino-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2-{[(2S,3R,4S,5R)-4-{[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy}-3-hydroxycyclohexyl]oxy}-2-(hydroxymethyl)oxane-3,4-diol; sulfuric acid

DATABASE IDS

• EC Number: 215-031-7
• CAS Number: 1263-89-4
• MDL Number: MFCD00079278
• Beilstein Number: 5715182

PROPERTIES

• Empirical Formula (Hill Notation): C23H45N5O14 · H2SO4
• Purity: >98.0% (TLC)
• Solubility: H2O: soluble50 mg/mL, slightly turbid, colorless
• RTECS: WK2320000
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.

Description (简体中文)

Biochem/physiol Actions
Paromomycin inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and leads to cell death.