2-(Trimethylsilyl)ethanethiol

• Catalog No.: 92729
• CAS Number: 18143-30-1
• M. F.: C5H14SSi
• M. W.: 134.31516
• Purity: ≥97.0% (GC)

SYNONYMS

• Title: 2-(三甲基硅烷)乙硫醇
• IUPAC name: 2-(trimethylsilyl)ethane-1-thiol
• IUPAC Traditional name: 2-(trimethylsilyl)ethanethiol
• Synonyms: (2-巯基乙基)三甲基硅烷; (2-Mercaptoethyl)trimethylsilane; BEST

DATABASE IDS

• CAS Number: 18143-30-1
• MDL Number: MFCD00077888
• Beilstein Number: 1732126

PROPERTIES

• Grade: purum
• Linear Formula: (CH3)3SiCH2CH2SH
• Purity: ≥97.0% (GC)
• Boiling Point: 144-146 °C(lit.)
• Boiling Point: 62-63 °C/43 mmHg(lit.)
• Density: 0.839 g/mL at 25 °C(lit.)
• Flash Point: 49 °C
• Flash Point: 120.2 °F
• Refractive Index: n20/D 1.454(lit.)
• Refractive Index: n20/D 1.455
• GHS Signal Word: Warning
• GHS Hazard statements: H226-H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
• GHS Precautionary statements: P261-P305 + P351 + P338
• RID/ADR: UN 1993 3/PG 3
• Risk Statements: 10-36/37/38
• RTECS: KJ2621000
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• Hazard Class: 3
• UN Number: 1993
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Reagent used for introducing the sulfhydryl group by alkylation, acylation, etc. followed by F--induced cleavage of the 2-(trimethylsilyl)ethyl group1,2; Cleavage to the thiol is also possible with other reagents3; Derivatization of anions is possible with the corresponding thiotosylate prepared with tosyl bromide4

Description (简体中文)

Other Notes
通过烷基化、酰化等反应，以及随后的 F- 诱导的 2-(三甲基硅基)乙基裂解反应引入巯基的试剂1,2；也可能被其他试剂裂解生成硫醇3；可能与对应的硫代甲苯磺酸酯发生阴离子衍生化反应，硫代甲苯磺酸酯可通过甲苯磺酰溴制备4