Cefotaxime sodium salt

• Catalog No.: 22128
• CAS Number: 64485-93-4
• M. F.: C16H16N5NaO7S2
• M. W.: 477.44731
• Purity: ≥98.0% (TLC)

SYNONYMS

• Title: Cefotaxime sodium salt 钠盐
• IUPAC name: sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• IUPAC Traditional name: sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Synonyms: Cefotaxim sodium salt 钠盐; Cefotaxim sodium salt

DATABASE IDS

• CAS Number: 64485-93-4
• EC Number: 264-915-9
• MDL Number: MFCD00079073
• Beilstein Number: 5711411

PROPERTIES

• Empirical Formula (Hill Notation): C16H16N5NaO7S2
• Impurities: ≤5% water
• Purity: ≥98.0% (TLC)
• Solubility: H2O: soluble50 mg/mL, clear, light yellow
• GHS Signal Word: Danger
• GHS Hazard statements: H317-H334
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P342 + P311
• Risk Statements: 42/43
• RTECS: XI0250000
• Safety Statements: 22-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Description (简体中文)

Other Notes
Broad spectrum third generation cephalosporin antibiotic.
Biochem/physiol Actions
Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.