5-Pregnen-3β-ol-20-one

• Catalog No.: 81630
• CAS Number: 145-13-1
• M. F.: C21H32O2
• M. W.: 316.47758

SYNONYMS

• IUPAC name: 1-[(1S,2R,5S,10S,11S,14S,15S)-5-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-7-en-14-yl]ethan-1-one
• IUPAC Traditional name: pregnenolone
• Synonyms: 3β-Hydroxy-5-pregnen-20-one; Pregnenolone

DATABASE IDS

• MDL Number: MFCD00003628
• CAS Number: 145-13-1
• EC Number: 205-647-4
• Beilstein Number: 2059026
• PubChem SID: 24887880

PROPERTIES

• Empirical Formula (Hill Notation): C21H32O2
• Grade: purum
• Gene Information: human ... SERPINA6(866)rat ... Ar(24208)
• Melting Point: 188-190 °C
• Optical Rotation: [α]20/D +27±1°, c = 1% in ethanol
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: TU5560700
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
One of a small number of "neurosteroids," steroids synthesized in the brain rather than peripheral sources. Decreased levels of these neurosteroids has been implicated in rodent cognitive decline with age, but studies in humans have been contradictory.1

Description (简体中文)

Biochem/physiol Actions
One of a small number of "neurosteroids," steroids synthesized in the brain rather than peripheral sources. Decreased levels of these neurosteroids has been implicated in rodent cognitive decline with age, but studies in humans have been contradictory.1