Trioxsalen

• Catalog No.: 92895
• CAS Number: 3902-71-4
• M. F.: C14H12O3
• M. W.: 228.24328
• Purity: ≥97.0% (HPLC)

SYNONYMS

• Title: 三甲沙林
• IUPAC name: 2,5,9-trimethyl-7H-furo[3,2-g]chromen-7-one
• IUPAC Traditional name: trioxsalen
• Synonyms: 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one; 4,5′,8-Trimethylpsoralen; 三甲补骨脂内酯; trisoralen; 4,5′,8-三甲基补骨脂素; TMP; 2,5,9-三甲基呋[3,2-g]苯并吡喃-7-酮

DATABASE IDS

• PubChem SID: 24889644
• Beilstein Number: 221723
• MDL Number: MFCD00005010
• EC Number: 223-459-0
• CAS Number: 3902-71-4

PROPERTIES

• Empirical Formula (Hill Notation): C14H12O3
• Purity: ≥97.0% (HPLC)
• Suitability: suitable for fluorescence
• Fluorescence: λex 321 nm; λem 445 nm in 10 mM Tris; 1 mM EDTA; pH 8.0; DNA
• Melting Point: 229-231 °C(lit.)
• Melting Point: 233-235 °C
• Solubility: DMSO: soluble
• Solubility: chloroform: soluble
• Solubility: methanol: soluble
• GHS Signal Word: Danger
• GHS Hazard statements: H314-H351
• European Hazard Symbols: Corrosive (C)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P280-P305 + P351 + P338-P310
• RID/ADR: UN 1759 8/PG 1
• Risk Statements: 34-40
• RTECS: LV1576000
• Safety Statements: 26-36/37/39-45
• Storage Temperature: 2-8°C
• Hazard Class: 8
• UN Number: 1759
• Packing Group: 1
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Photochemical crosslinker of DNA that has been used as a probe for nucleic acid structure and function. Trioxsalen has also been used to crosslink DNA onto mica surfaces.

Description (简体中文)

Biochem/physiol Actions
DNA 的光化学交联剂，可作为探针用于核酸结构和功能研究。三甲沙林也用于使 DNA 在云母表面交联。