Tobramycin

• Catalog No.: 89549
• CAS Number: 32986-56-4
• M. F.: C18H37N5O9
• M. W.: 467.51448
• Purity: ≥99.0% (TLC)

SYNONYMS

• IUPAC name: (2S,3R,4R,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol
• IUPAC Traditional name: (2S,3R,4R,5S,6R)-4-amino-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,5S,6R)-3-amino-6-(aminomethyl)-5-hydroxyoxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-6-(hydroxymethyl)oxane-3,5-diol
• Synonyms: O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine

DATABASE IDS

• MDL Number: MFCD00077885
• Beilstein Number: 1357507
• CAS Number: 32986-56-4
• EC Number: 251-322-5

PROPERTIES

• Empirical Formula (Hill Notation): C18H37N5O9
• Impurities: ≤8% water
• Purity: ≥99.0% (TLC)
• Solubility: H2O: soluble50 mg/mL, clear, faintly yellow
• RTECS: WK2100000
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Tobramycin is an aminoglycoside. Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Spectrum of Activity: Gram negative bacteria. Not effective against Enterococci.

Description (简体中文)

Biochem/physiol Actions
Tobramycin is an aminoglycoside. Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Spectrum of Activity: Gram negative bacteria. Not effective against Enterococci.