Home > Compound List > Product Information
Acetoacetyl coenzyme A sodium salt hydrate_Molecular_structure_CAS_1420-36-6(freeacid))
Click picture or here to close

Acetoacetyl coenzyme A sodium salt hydrate

Catalog No. 00062 Name Sigma Aldrich
CAS Number 1420-36-6(freeacid) Website http://www.sigmaaldrich.com
M. F. C25H37N7Na3O18P3S Telephone 1-800-521-8956
M. W. 917.552973 Fax
Purity ~95% (HPLC) Email
Storage Chembase ID: 133385

SYNONYMS

Title
Acetoacetyl coenzyme A 钠盐 水合物
IUPAC name
trisodium (2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-[({hydroxy[(3-hydroxy-2,2-dimethyl-3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propyl phosphonato)oxy]phosphoryl}oxy)methyl]oxolan-3-yl phosphate
IUPAC Traditional name
trisodium (2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-({[hydroxy(3-hydroxy-2,2-dimethyl-3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propyl phosphonato)oxyphosphoryl]oxy}methyl)oxolan-3-yl phosphate
Synonyms
Acetoacetyl-CoANa3

DATABASE IDS

CAS Number 1420-36-6(freeacid)

PROPERTIES

Empirical Formula (Hill Notation) C25H40N7O18P3S · xNa+ · yH2O
Impurities ≤1% ATP (HPLC)
Impurities ≤6% coenzyme A (HPLC)
Impurities ≤8% coenzyme A oxidized (HPLC)
Purity ~95% (HPLC)
Solubility H2O: soluble50 mg/mL, clear, colorless to faintly yellow
MSDS Link Download
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Application
Substrate for acetoacetyl-CoA thiolase EC 2.3.1.9; Role in the biosynthesis of nonactin.
Acetoacetyl coenzyme A (Acetoacetyl-CoA) may be used as a substrate for a number of enzymes including; acetoacetyl-CoA thiolase (EC 2.3.1) which produces acetyl-CoA in reverse condensation reaction and (3-Hydroxy-3-methylglutaryl coenzyme A (CoA) synthase (HMGCS)) which produces 3-hydroxy-3-methylglutaryl (HMG)-CoA in the mevalonate pathway leading to terpenoid biosynthesis. Acetoacetyl-CoA is also a precursor of poly-β-hydroxybutyrate polymers in microorganisms.
Other Notes
Substrate for acetoacetyl-CoA thiolase EC 2.3.1.91; Role in the biosynthesis of nonactin2
Description (简体中文)
Application
Substrate for acetoacetyl-CoA thiolase EC 2.3.1.9; Role in the biosynthesis of nonactin.
Acetoacetyl coenzyme A (Acetoacetyl-CoA) may be used as a substrate for a number of enzymes including; acetoacetyl-CoA thiolase (EC 2.3.1) which produces acetyl-CoA in reverse condensation reaction and (3-Hydroxy-3-methylglutaryl coenzyme A (CoA) synthase (HMGCS)) which produces 3-hydroxy-3-methylglutaryl (HMG)-CoA in the mevalonate pathway leading to terpenoid biosynthesis. Acetoacetyl-CoA is also a precursor of poly-β-hydroxybutyrate polymers in microorganisms.
Other Notes
Substrate for acetoacetyl-CoA thiolase EC 2.3.1.91; Role in the biosynthesis of nonactin2

REFERENCES