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Flunarizine dihydrochloride

Catalog No. 46392 Name Sigma Aldrich
CAS Number 30484-77-6 Website http://www.sigmaaldrich.com
M. F. C26H28Cl2F2N2 Telephone 1-800-521-8956
M. W. 477.4167264 Fax
Purity ≥98.0% (TLC) Email
Storage Chembase ID: 103955

SYNONYMS

Title
氟桂嗪 二盐酸盐
IUPAC name
1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-en-1-yl)piperazine dihydrochloride
IUPAC Traditional name
1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-en-1-yl)piperazine dihydrochloride
Synonyms
1-[双(4-氟苯基)甲基]-4-(3-苯基-2-丙烯基)哌嗪 二盐酸盐
1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride

DATABASE IDS

Beilstein Number 4284243
CAS Number 30484-77-6
EC Number 250-216-6
MDL Number MFCD00058198

PROPERTIES

Empirical Formula (Hill Notation) C26H26F2N2 · 2HCl
Purity ≥98.0% (TLC)
Solubility chloroform/methanol (9:1): soluble50 mg/mL, clear, colorless
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Risk Statements 22
RTECS TK9187000
German water hazard class 3

DETAILS

Description (English)
Other Notes
Calcium antagonist. Selectively blocks T-type calcium channels1
Biochem/physiol Actions
Blocks T-type Ca2+/Na+ channels; inhibits K+-induced catecholamine release from chromaffin cells
Description (简体中文)
Other Notes
Calcium antagonist. Selectively blocks T-type calcium channels1
Biochem/physiol Actions
阻断 T 型 Ca2+/Na+ 通道;抑制嗜铬细胞中由 K+ 诱导的儿茶酚胺释放。

REFERENCES