cis-4-Hydroxy-L-proline

• Catalog No.: 56248
• CAS Number: 618-27-9
• M. F.: C5H9NO3
• M. W.: 131.12986
• Purity: ≥99.0% (NT)

SYNONYMS

• Title: 顺式-4-羟基-L-脯氨酸
• IUPAC name: (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid
• IUPAC Traditional name: L-hydroxyproline
• Synonyms: (2S,4S)-(-)-4-羟基-2-吡咯烷羧酸; CHP; (2S,4S)-(-)-4-Hydroxy-2-pyrrolidinecarboxylic acid

DATABASE IDS

• EC Number: 210-542-1
• PubChem SID: 24880039
• CAS Number: 618-27-9
• Beilstein Number: 81440
• MDL Number: MFCD00064319

PROPERTIES

• Empirical Formula (Hill Notation): C5H9NO3
• Grade: puriss.
• Purity: ≥99.0% (NT)
• Melting Point: 253-257 °C (dec.)
• Melting Point: 257 °C (dec.)(lit.)
• Optical Rotation: [α]20/D -59±1°, c = 1% in H2O
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Proline antagonist in collagen synthesis. Inhibits human skin fibroblast growth and collagen production in culture1; Specifically inhibits cultured tumour cells that synthesize basement-membrane collagen2,3; Its incorporation inhibits secretion of procollagen4

Description (简体中文)

Other Notes
Proline antagonist in collagen synthesis. Inhibits human skin fibroblast growth and collagen production in culture1; Specifically inhibits cultured tumour cells that synthesize basement-membrane collagen2,3; Its incorporation inhibits secretion of procollagen4