5-Hydroxyindole-2-carboxylic acid

• Catalog No.: 55355
• CAS Number: 21598-06-1
• M. F.: C9H7NO3
• M. W.: 177.15678
• Purity: ≥97.0% (T)

SYNONYMS

• Title: 5-羟基吲哚-2-甲酸
• IUPAC name: 5-hydroxy-1H-indole-2-carboxylic acid
• IUPAC Traditional name: 5-hydroxy-1H-indole-2-carboxylic acid
• Synonyms: NSC 117338

DATABASE IDS

• PubChem SID: 24879337
• EC Number: 244-468-6
• Beilstein Number: 153214
• MDL Number: MFCD00005615
• CAS Number: 21598-06-1

PROPERTIES

• Empirical Formula (Hill Notation): C9H7NO3
• Grade: purum
• Purity: ≥97.0% (T)
• Melting Point: 249 °C (dec.)(lit.)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Application

• Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents
• Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors1
• Reactant for preparation of melanins as novel nature-inspired radioprotectors2
• Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity3
• Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal transducer and activator of transcription 3 (Stat3)4
• Reactant for preparation of oxadiazole analogs as nonpeptidic SH2 inhibitors of tyrosine kinase ZAP-705

Description (简体中文)

Application

• Reactant for preparation of indole C5-O-substituted seco-cyclopropylindole analogs as potential anticancer agents
• Reactant for microwave combinatorial synthesis of indolic arylpiperazine derivatives as ligands for 5-HT1A, 5-HT2A, and 5-HT2C receptors1
• Reactant for preparation of melanins as novel nature-inspired radioprotectors2
• Reactant for preparation of 5-Hydroxyindole-2-carboxylic acid amides as histamine-3 receptor inverse agonists for the treatment of obesity3
• Reactant for preparation of conformationally constrained peptidomimetic inhibitors of signal transducer and activator of transcription 3 (Stat3)4
• Reactant for preparation of oxadiazole analogs as nonpeptidic SH2 inhibitors of tyrosine kinase ZAP-705