Pimaricin preparation

• Catalog No.: 80482
• CAS Number: 7681-93-8
• M. F.: C33H47NO13
• M. W.: 665.72518
• Purity: ~90% (N)

SYNONYMS

• Title: 游霉素 制备
• IUPAC name: (1R,3S,5R,7R,12R,22R,24S,25R,26S)-22-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0^5,^7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• IUPAC Traditional name: (1R,3S,5R,7R,12R,22R,24S,25R,26S)-22-{[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-1,3,26-trihydroxy-12-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.0^5,^7]octacosa-8,14,16,18,20-pentaene-25-carboxylic acid
• Synonyms: Natamycin preparation; 那他霉素 制备

DATABASE IDS

• PubChem SID: 24887548
• CAS Number: 7681-93-8
• Beilstein Number: 1614878
• MDL Number: MFCD00135085

PROPERTIES

• Empirical Formula (Hill Notation): C33H47NO13
• Purity: ~90% (N)
• Quality: aqueous suspension 2.5%
• Quality: sterile
• Density: 1.0 g/mL at 20 °C(lit.)
• Personal Protective Equipment: Eyeshields, Gloves
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane.1
Other Notes
Polyene antibiotic, review2

Description (简体中文)

Biochem/physiol Actions
An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane.1
Other Notes
Polyene antibiotic, review2