Clindamycin hydrochloride

• Catalog No.: 27543
• CAS Number: 21462-39-5
• M. F.: C18H34Cl2N2O5S
• M. W.: 461.44396
• Purity: ≥96.0% (TLC)

SYNONYMS

• IUPAC name: (2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide hydrochloride
• IUPAC Traditional name: cleocin T gel hydrochloride
• Synonyms: Cleocin; (7S)-7-Chloro-7-deoxylincomycin hydrochloride

DATABASE IDS

• CAS Number: 21462-39-5
• Beilstein Number: 4070786
• MDL Number: MFCD07793327
• EC Number: 244-398-6

PROPERTIES

• Empirical Formula (Hill Notation): C18H33ClN2O5S · HCl
• Purity: ≥96.0% (TLC)
• Solubility: H2O: soluble50 mg/mL, clear, colorless
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: GF2275000
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Other Notes
Antibacterial and antiprotozoal antibiotic of the licosamide class.
Review1
Biochem/physiol Actions
Spectrum of Activity: Gram positive cocci and taxoplasma. Especially active against anaerobic bacteria.Mode of Action: Inhibits protein synthesis in bacteria by binding the 50s ribosomal subunit.Clindamycin is a semi-synthetic, lincosamide antibiotic that is prepared from lincomycin. It inhibits bacterial protein synthesis by hydrogen bond interactions with the 23S rRNA component of the 50S ribosomal subunit thus inducing dissociation of the peptidyl-t-RNA complex. Antibacterial and antiprotozoal antibiotic.

Description (简体中文)

Other Notes
Antibacterial and antiprotozoal antibiotic of the licosamide class.
Review1
Biochem/physiol Actions
Spectrum of Activity: Gram positive cocci and taxoplasma. Especially active against anaerobic bacteria.Mode of Action: Inhibits protein synthesis in bacteria by binding the 50s ribosomal subunit.Clindamycin is a semi-synthetic, lincosamide antibiotic that is prepared from lincomycin. It inhibits bacterial protein synthesis by hydrogen bond interactions with the 23S rRNA component of the 50S ribosomal subunit thus inducing dissociation of the peptidyl-t-RNA complex. Antibacterial and antiprotozoal antibiotic.