5-Fluorouracil

• Catalog No.: 47576
• CAS Number: 51-21-8
• M. F.: C4H3FN2O2
• M. W.: 130.0772232
• Purity: ≥99.0% (HPLC)

SYNONYMS

• Title: 5-氟脲嘧啶
• IUPAC name: 5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4-dione
• IUPAC Traditional name: fluorouracil
• Synonyms: 2,4-二羟基-5-氟嘧啶; 5-氟-2,4(1H,3H)-嘧啶二酮; 2,4-Dihydroxy-5-fluoropyrimidine; 5-Fluoro-2,4(1H,3H)-pyrimidinedione; 5-FU

DATABASE IDS

• CAS Number: 51-21-8
• Beilstein Number: 127172
• EC Number: 200-085-6
• PubChem SID: 24871165
• MDL Number: MFCD00006018

PROPERTIES

• Empirical Formula (Hill Notation): C4H3FN2O2
• Purity: ≥99.0% (HPLC)
• Melting Point: 282-286 °C (dec.)(lit.)
• Melting Point: 282-286 °C (dec.)
• Solubility: H2O: soluble10 mg/mL, clear
• European Hazard Symbols: Harmful (Xn)
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 22
• RTECS: YR0350000
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Potent antineoplastic agent. Its determination in tissue with microbore HPLC and fluorescence detection1; Metabolised to fluoro-2′-deoxyuridine monophosphate which inhibits DNA synthesis by blocking thymidylate synthetase2

Description (简体中文)

Other Notes
Potent antineoplastic agent. Its determination in tissue with microbore HPLC and fluorescence detection1; Metabolised to fluoro-2′-deoxyuridine monophosphate which inhibits DNA synthesis by blocking thymidylate synthetase2