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Progesterone

Catalog No. 81702 Name Sigma Aldrich
CAS Number 57-83-0 Website http://www.sigmaaldrich.com
M. F. C21H30O2 Telephone 1-800-521-8956
M. W. 314.4617 Fax
Purity ≥97.0% (HPLC) Email
Storage Chembase ID: 279

SYNONYMS

Title
孕酮
IUPAC name
(1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
IUPAC Traditional name
progesterone
Synonyms
孕烯二酮
4-pregnene-3,20-dione

DATABASE IDS

MDL Number MFCD00003658
CAS Number 57-83-0
EC Number 200-350-6
Beilstein Number 1915950

PROPERTIES

Empirical Formula (Hill Notation) C21H30O2
Grade purum
Loss on Drying ≤0.5% loss on drying
Purity ≥97.0% (HPLC)
Gene Information human ... ESR1(2099), PGR(5241)
Melting Point 128-132 °C(lit.)
Melting Point 128-132 °C
Optical Rotation [α]20/D +190±4°, c = 1% in ethanol
GHS Pictograms GHS08
GHS Signal Word Warning
GHS Hazard statements H351
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements P281
Risk Statements 40
RTECS TW0175000
Safety Statements 36/37
German water hazard class 3

DETAILS

Description (English)
Other Notes
Steroid hormone produced by the corpus luteum.
Biochem/physiol Actions
Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.
Description (简体中文)
Other Notes
由卵巢黄体产生的类固醇激素。
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。

REFERENCES