O-Acetyl-L-carnitine hydrochloride

• Catalog No.: 00985
• CAS Number: 5080-50-2
• M. F.: C9H18ClNO4
• M. W.: 239.69652
• Purity: ≥99.0% (AT)

SYNONYMS

• IUPAC name: [(2R)-2-(acetyloxy)-3-carboxypropyl]trimethylazanium chloride
• IUPAC Traditional name: O-acetylcarnitinium chloride
• Synonyms: (R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride; R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride; ALC; ALCAR

DATABASE IDS

• MDL Number: MFCD00082230
• CAS Number: 5080-50-2
• Beilstein Number: 4340103

PROPERTIES

• Empirical Formula (Hill Notation): C9H17NO4 · HCl
• Loss on Drying: ≤0.5% loss on drying
• Purity: ≥99.0% (AT)
• Optical Rotation: [α]20/D -29±1°, c = 1% in H2O
• Solubility: H2O: soluble0.1 g/mL, clear, colorless
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Transmembrane action potential studies1
Biochem/physiol Actions
Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

Description (简体中文)

Other Notes
Transmembrane action potential studies1
Biochem/physiol Actions
Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.