Piericidin A from microbial source_Molecular_structure_CAS_2738-64-9)

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Piericidin A from microbial source
Catalog No.	P4368	Name	Sigma Aldrich
CAS Number	2738-64-9	Website	http://www.sigmaaldrich.com
M. F.	C25H37NO4	Telephone	1-800-521-8956
M. W.	415.56558	Fax
Purity	>95% (HPLC)	Email
Storage		Chembase ID: 156069

PRICE

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SYNONYMS

IUPAC name

2-[(9R,10R)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl]-5,6-dimethoxy-3-methylpyridin-4-ol

IUPAC Traditional name

2-[(9R,10R)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl]-5,6-dimethoxy-3-methylpyridin-4-ol

Synonyms

4-Pyridinol,2-(10-hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraenyl)-5,6-dimethoxy- [R-[R*,R*-(all-E)]]-3-methyl-

SN 198E

Piericidin A1

2,6,9,11-Tridecatetraen-4-ol,13-(4-hydrox-5,6-dimethoxy-3-methyl-2-pyridyl)-3,5,7,11-tetramethyl-(all-E)-(4R,5R)

Shaoguamycin B

DATABASE IDS

PubChem SID	24898532
MDL Number	MFCD01677956
CAS Number	2738-64-9

PROPERTIES

Empirical Formula (Hill Notation)	C25H37NO4
Purity	>95% (HPLC)
Shipped in	wet ice
Apperance	DMSO solution
Flash Point	85 °C
Flash Point	185 °F
European Hazard Symbols	Harmful (Xn)
MSDS Link	Download
Personal Protective Equipment	Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Risk Statements	20/21/22
Safety Statements	36/37
Storage Temperature	2-8°C
German water hazard class	1

DETAILS

Description (English)

Biochem/physiol Actions
Piericidin A is a potent inhibitor of the mitochondrial and bacterial type I NADH-ubiquinone oxireductase (Complex I). It is considered to bind to the ubiquinone binding sites of the enzyme. Peiricidin A inactivation of complex I completely prevents NADH-induced proton translocation in the NADH-endogenous ubiquinone reductase reaction.

Description (简体中文)