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GW2974

Catalog No. G0668 Name Sigma Aldrich
CAS Number 202272-68-2 Website http://www.sigmaaldrich.com
M. F. C23H21N7 Telephone 1-800-521-8956
M. W. 395.45974 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 156065

SYNONYMS

IUPAC name
4-N-(1-benzyl-1H-indazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
IUPAC Traditional name
4-N-(1-benzylindazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
Synonyms
N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido-[3,4-d]-pyrimidine-4,6-diamine

DATABASE IDS

MDL Number MFCD04974495
PubChem SID 24278451
CAS Number 202272-68-2

PROPERTIES

Empirical Formula (Hill Notation) C23H21N7
Purity ≥98% (HPLC)
Gene Information human ... EGFR(1956), ERBB2(2064)
Apperance yellow solid
Solubility DMSO: ≥20 mg/mL
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline
Description (简体中文)
Biochem/physiol Actions
Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline

REFERENCES