GW2974

• Catalog No.: G0668
• CAS Number: 202272-68-2
• M. F.: C23H21N7
• M. W.: 395.45974
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-N-(1-benzyl-1H-indazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
• IUPAC Traditional name: 4-N-(1-benzylindazol-5-yl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
• Synonyms: N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido-[3,4-d]-pyrimidine-4,6-diamine

DATABASE IDS

• MDL Number: MFCD04974495
• PubChem SID: 24278451
• CAS Number: 202272-68-2

PROPERTIES

• Empirical Formula (Hill Notation): C23H21N7
• Purity: ≥98% (HPLC)
• Gene Information: human ... EGFR(1956), ERBB2(2064)
• Apperance: yellow solid
• Solubility: DMSO: ≥20 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline

Description (简体中文)

Biochem/physiol Actions
Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline