Tenoxicam

• Catalog No.: DB00469
• CAS Number: 59804-37-4
• M. F.: C13H11N3O4S2
• M. W.: 337.37414

SYNONYMS

• IUPAC name: (3Z)-3-{hydroxy[(pyridin-2-yl)amino]methylidene}-2-methyl-2H,3H,4H-1$l^{6},5,2-thieno[2,3-e][1$l^{6},2]thiazine-1,1,4-trione
• IUPAC Traditional name: tenoxicam
• Brand Name: Apo-Tenoxicam; Novo-Tenoxicam; Tilcotil
• Synonyms: Tenoxicamum [INN-Latin]

DATABASE IDS

• PubChem CID: 5312154
• PubChem SID: 46507303
• CAS Number: 59804-37-4

PROPERTIES

• Hydrophobicity(logP): 1.9
• Solubility: 14.1 mg/L

DETAILS

Description (English)

• Drug Groups: approved
• Description: Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
• Indication: For the treatment of rheumatoid arthritis, osteoarthritis, backache, and pain.
• Pharmacology: Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
• Affected Organisms: Humans and other mammals
• Biotransformation: Tenoxicam is metabolized in the liver to several pharmacologically inactive metabolites (mainly 5'-hydroxy-tenoxicam).
• Absorption: Oral absorption of tenoxicam is rapid and complete (absolute bioavailability 100%).
• Half Life: 72 hours (range 59 to 74 hours)
• Protein Binding: 99%