Nicotinamide

• Catalog No.: 72340
• CAS Number: 98-92-0
• M. F.: C6H6N2O
• M. W.: 122.12464
• Purity: ≥99.5% (HPLC)

SYNONYMS

• Title: 尼克酰胺
• IUPAC name: pyridine-3-carboxamide
• IUPAC Traditional name: nicotinamide
• Synonyms: 维生素 PP; 维生素 B3; Nicotinic acid amide; Pyridine-3-carboxylic acid amide; Vitamin B3; 吡啶-3-甲酰胺; 烟碱酰胺; 烟酰胺; niacinamide; Vitamin PP

DATABASE IDS

• EC Number: 202-713-4
• MDL Number: MFCD00006395
• CAS Number: 98-92-0
• Beilstein Number: 383619
• PubChem SID: 24886391

PROPERTIES

• Antion Traces: chloride (Cl-): ≤50 mg/kg
• Antion Traces: sulfate (SO42-): ≤50 mg/kg
• Cation Traces: Ca: ≤10 mg/kg
• Cation Traces: Cd: ≤5 mg/kg
• Cation Traces: Co: ≤5 mg/kg
• Cation Traces: Cr: ≤5 mg/kg
• Cation Traces: Cu: ≤5 mg/kg
• Cation Traces: Fe: ≤5 mg/kg
• Cation Traces: K: ≤50 mg/kg
• Cation Traces: Mg: ≤5 mg/kg
• Cation Traces: Mn: ≤5 mg/kg
• Cation Traces: Na: ≤50 mg/kg
• Cation Traces: Ni: ≤5 mg/kg
• Cation Traces: Pb: ≤5 mg/kg
• Cation Traces: Zn: ≤5 mg/kg
• Empirical Formula (Hill Notation): C6H6N2O
• Ignition Residue: ≤0.2%
• Loss on Drying: ≤0.2% loss on drying, 20 °C (HV)
• Purity: ≥99.5% (HPLC)
• Gene Information: human ... PARP1(142), SIRT2(22933)
• Flash Point: 150 °C
• Flash Point: 302 °F
• Melting Point: 128-131 °C(lit.)
• Melting Point: 128-131 °C
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: QS3675000
• Safety Statements: 26-36
• German water hazard class: 1

DETAILS

Description (English)

Other Notes
Coenzymes and Cofactors, vol. 2: Pyridine Nucleotide Coenzymes1,2
Biochem/physiol Actions
Nicotinamide (Niacinamide) (Nam) is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). Nicotinamide may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule.
Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Description (简体中文)

Other Notes
Coenzymes and Cofactors, vol. 2: Pyridine Nucleotide Coenzymes1,2
Biochem/physiol Actions
Nicotinamide (Niacinamide) (Nam) is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). Nicotinamide may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule.
Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor