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2′-Azido-2′-deoxyuridine_Molecular_structure_CAS_26929-65-7)
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2′-Azido-2′-deoxyuridine

Catalog No. 11544 Name Sigma Aldrich
CAS Number 26929-65-7 Website http://www.sigmaaldrich.com
M. F. C9H11N5O5 Telephone 1-800-521-8956
M. W. 269.21414 Fax
Purity ≥98.0% (N) Email
Storage Chembase ID: 156028

SYNONYMS

IUPAC name
1-[(2R,3R,4S,5R)-3-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
IUPAC Traditional name
1-[(2R,3R,4S,5R)-3-azido-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-pyrimidine-2,4-dione
Synonyms
N3-dU

DATABASE IDS

CAS Number 26929-65-7
PubChem SID 24847215
MDL Number MFCD00043045
Beilstein Number 4204828
EC Number 248-113-6

PROPERTIES

Empirical Formula (Hill Notation) C9H11N5O5
Purity ≥98.0% (N)
Melting Point 149-153 °C
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Application
2′-Azido-2′-deoxyuridine (N3-dU) upon phosphorylation to 2′-azido-2′-deoxyuridine 5′-diphosphate (N3dUDP) becomes a mechanistic inhibitor of bacterial ribonucleoside diphosphate reductase (RDPR). N3-dU has recently been evaluated for its potential use as a sensitive multi-spectroscopic probe for nucleic acids
Description (简体中文)
Application
2′-Azido-2′-deoxyuridine (N3-dU) upon phosphorylation to 2′-azido-2′-deoxyuridine 5′-diphosphate (N3dUDP) becomes a mechanistic inhibitor of bacterial ribonucleoside diphosphate reductase (RDPR). N3-dU has recently been evaluated for its potential use as a sensitive multi-spectroscopic probe for nucleic acids

REFERENCES