D-Cycloserine

• Catalog No.: 30020
• CAS Number: 68-41-7
• M. F.: C3H6N2O2
• M. W.: 102.09194
• Purity: ≥96.0% (NT)

SYNONYMS

• Title: D-环丝氨酸
• IUPAC name: (4R)-4-amino-1,2-oxazolidin-3-one
• IUPAC Traditional name: cycloserine
• Synonyms: 4-氨基-3-异噁唑烷酮; 4-Amino-3-isoxazolidinone; (R)-4-Amino-3-isoxazolidone; (R)-4-氨基-3-异噁唑烷酮

DATABASE IDS

• MDL Number: MFCD00005353
• CAS Number: 68-41-7
• PubChem SID: 24858076
• Beilstein Number: 80798
• EC Number: 200-688-4

PROPERTIES

• Storage Temperature: -20°C
• German water hazard class: 2
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: NY2975000
• Empirical Formula (Hill Notation): C3H6N2O2
• Purity: ≥96.0% (NT)
• Melting Point: 147 °C (dec.)(lit.)
• Optical Rotation: [α]20/D +115.0±5.0°, c = 2% in H2O

DETAILS

Description (简体中文)

Application
Cycloserine is used to inhibit various enzymes.
Biochem/physiol Actions
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
作用方式：抑制细胞壁的生物合成（D-Ala 肽键的形成）。也会阻碍 D-Ala 向 L-Ala 的转化。抑菌。 抗性机理：干扰 D-Ala 转运。
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic. Mode of Resistance: D-Ala transport interference.
Other Notes
D-Cycloserine acts as inhibitor of various enzymes.1
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Description (English)

Application
Cycloserine is used to inhibit various enzymes.
Biochem/physiol Actions
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic.Mode of Resistance: D-Ala transport interference.
Partial agonist at the glycine modulatory site of NMDA glutamatergic receptors; antibiotic against Gram-negative bacteria.
Mode of Action: Inhibits cell wall biosynthesis (D-Ala peptide bond formation). Also prevents conversion of D-Ala to L-Ala. Bacteriostatic. Mode of Resistance: D-Ala transport interference.
Other Notes
D-Cycloserine acts as inhibitor of various enzymes.1
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information