Carboxymethyl-β-cyclodextrin sodium salt

• Catalog No.: 21906
• M. F.: C56H84O49
• M. W.: 1541.23676

SYNONYMS

• IUPAC name: 2-{[(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,37S,38S,39S,40S,41S,42S,43S,44S,45S,46S,47S,48S,49S)-10,15,20,25,30,35-hexakis[(carboxymethoxy)methyl]-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecahydroxy-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.2^3,^6.2^8,^1^1.2^1^3,^1^6.2^1^8,^2^1.2^2^3,^2^6.2^2^8,^3^1]nonatetracontan-5-yl]methoxy}acetic acid
• IUPAC Traditional name: {[(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36S,37S,38S,39S,40S,41S,42S,43S,44S,45S,46S,47S,48S,49S)-10,15,20,25,30,35-hexakis[(carboxymethoxy)methyl]-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecahydroxy-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.2^3,^6.2^8,^1^1.2^1^3,^1^6.2^1^8,^2^1.2^2^3,^2^6.2^2^8,^3^1]nonatetracontan-5-yl]methoxy}acetic acid

DATABASE IDS

• PubChem SID: 24853105
• MDL Number: MFCD00285608

PROPERTIES

• Impurities: 10% water
• Melting Point: ~245 °C (dec.)
• Solubility: H2O: soluble50 mg/mL, clear, colorless
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Analysis Note
average degree of substitution, DS ~3
Application
Cyclodextrins (CD) are cyclic oligosaccharides composed of D-glucose units connected via α(1→4) glycosidic bonds. Common cyclodextrins contain six (α-CD); seven (β-CD) or eight (gamma-CD) D-glucose units. Cyclodextrins are sometimes derivitized through esterification at positions two, three and/or six.Carboxymethyl-β-cyclodextrin (CMBCD) is used in the development of recognition and separation technologies to resolve enantiomers based on chiral properties and size. Carboxymethyl-β-cyclodextrin is used in chiral selection and separation by capillary electrophoresis. Carboxymethyl-β-cyclodextrin is used in the development of drug delivery vehicles such as nanocarriers and as a nucleic acid transfection agent.

Description (简体中文)

Analysis Note
average degree of substitution, DS ~3
Application
Cyclodextrins (CD) are cyclic oligosaccharides composed of D-glucose units connected via α(1→4) glycosidic bonds. Common cyclodextrins contain six (α-CD); seven (β-CD) or eight (gamma-CD) D-glucose units. Cyclodextrins are sometimes derivitized through esterification at positions two, three and/or six.Carboxymethyl-β-cyclodextrin (CMBCD) is used in the development of recognition and separation technologies to resolve enantiomers based on chiral properties and size. Carboxymethyl-β-cyclodextrin is used in chiral selection and separation by capillary electrophoresis. Carboxymethyl-β-cyclodextrin is used in the development of drug delivery vehicles such as nanocarriers and as a nucleic acid transfection agent.