Oligomycin A

• Catalog No.: 75351
• CAS Number: 579-13-5
• M. F.: C45H74O11
• M. W.: 791.06246
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: (5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-2,26-dioxaspiro[bicyclo[23.3.1]nonacosane-27,2'-oxane]-4,18,20-triene-3,9,13-trione
• IUPAC Traditional name: (5'R,6R,7S,8R,10R,11R,12S,14S,15R,16S,28R,29S)-22-ethyl-7,11,14,15-tetrahydroxy-6'-[(2S)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-2,26-dioxaspiro[bicyclo[23.3.1]nonacosane-27,2'-oxane]-4,18,20-triene-3,9,13-trione

DATABASE IDS

• MDL Number: MFCD00065705
• CAS Number: 579-13-5
• PubChem SID: 24886820
• Beilstein Number: 5702132
• EC Number: 209-437-3

PROPERTIES

• Empirical Formula (Hill Notation): C45H74O11
• Purity: ≥95% (HPLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 22
• RTECS: RK3328000
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Inhibits the growth of Rhodotorula glutinis, Aspergillus niger and other moulds3
Application
Oligomycin is used to inhibit membrane bount mitochondrial ATP synthase. It is used to inhibit sucrose synthesis and 14C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O2 and CO2 in the cat 1,2.
Biochem/physiol Actions
Oligomycin inhibits membrane bound mitochondrial ATP synthase (ATPase), proton channel (pump, FO subunit) blockers thereby inhibiting oxidative phosphorylation and the electron transport chain.

Description (简体中文)

Other Notes
Inhibits the growth of Rhodotorula glutinis, Aspergillus niger and other moulds3
Application
Oligomycin is used to inhibit membrane bount mitochondrial ATP synthase. It is used to inhibit sucrose synthesis and 14C translocation in sunflower leaves, to study antibiotic resistance, and to study carotid chemoreceptor responses to O2 and CO2 in the cat 1,2.
Biochem/physiol Actions
Oligomycin inhibits membrane bound mitochondrial ATP synthase (ATPase), proton channel (pump, FO subunit) blockers thereby inhibiting oxidative phosphorylation and the electron transport chain.