Quinine

• Catalog No.: 22620
• CAS Number: 130-95-0
• M. F.: C20H24N2O2
• M. W.: 324.41676
• Purity: ≥98.0% (dried material, NT)

SYNONYMS

• Title: 奎宁
• IUPAC name: (R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol
• IUPAC Traditional name: quinine

DATABASE IDS

• CAS Number: 130-95-0
• PubChem SID: 24853550
• MDL Number: MFCD00198096
• Beilstein Number: 91867
• EC Number: 205-003-2

PROPERTIES

• Empirical Formula (Hill Notation): C20H24N2O2
• Impurities: ≤5% dihydroquinine (HPLC)
• Loss on Drying: ≤1% loss on drying, 110 °C
• Purity: ≥98.0% (dried material, NT)
• Suitability: suitable for fluorescence
• Gene Information: human ... ABCB1(5243), CYP2C9(1559), CYP2D6(1565)rat ... Cyp2d1(266684), Cyp2d2(25053), Cyp2d3(24303), Cyp2d4v1(171522)
• Fluorescence: λex 347 nm; λem 448 nm in 0.5 M sulfuric acid
• Melting Point: 173-175 °C(lit.)
• Optical Rotation: [α]20/D -126±5°, c = 1% in chloroform
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H317-H319-H334-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P280-P305 + P351 + P338-P342 + P311
• Risk Statements: 36/37/38-42/43
• RTECS: VA6020000
• Safety Statements: 22-26-36/37-45
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Potassium channel blocker
Other Notes
Chiral catalyst, used e.g. in highly enantioselective [2+2] cycloadditions1,2; In additions of diethylzinc to aldehydes.3

Description (简体中文)

Biochem/physiol Actions
钾通道阻断剂。
Other Notes
Chiral catalyst, used e.g. in highly enantioselective [2+2] cycloadditions1,2; In additions of diethylzinc to aldehydes.3