1α,25-Dihydroxyvitamin D2

• Catalog No.: 17944
• CAS Number: 60133-18-8
• M. F.: C28H44O3
• M. W.: 428.64716
• Purity: ≥97.0% (sum of vitamin and previtamin, HPLC)

SYNONYMS

• IUPAC name: (1R,3S)-5-{2-[(1R,3aS,7aR)-1-[(2R,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• IUPAC Traditional name: (1R,3S)-5-{2-[(1R,3aS,7aR)-1-[(2R,5S)-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-hexahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
• Synonyms: 1α,25-Dihydroxycalciferol

DATABASE IDS

• MDL Number: MFCD00869499
• Beilstein Number: 5635017
• PubChem SID: 24850813
• CAS Number: 60133-18-8

PROPERTIES

• Empirical Formula (Hill Notation): C28H44O3
• Purity: ≥97.0% (sum of vitamin and previtamin, HPLC)
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H311-H331-H361
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P261-P280-P301 + P310-P311
• RID/ADR: UN 2811 6.1/PG 2
• Risk Statements: 63-23/24/25
• Safety Statements: 36/37-45
• Storage Temperature: -70°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Ergocalciferol (vitamin D2) is activated in vivo by hydroxylation to 25-hydroxyergocalciferol and 1α,25-dihydroxycalciferol. Activated Vitamin D2 molecules may be used in a wide range of studies to assess their effects on functions such as immune function and calcium homeostasis.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 17944.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Description (简体中文)

Biochem/physiol Actions
Ergocalciferol (vitamin D2) is activated in vivo by hydroxylation to 25-hydroxyergocalciferol and 1α,25-dihydroxycalciferol. Activated Vitamin D2 molecules may be used in a wide range of studies to assess their effects on functions such as immune function and calcium homeostasis.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 17944.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.