Naringin

• Catalog No.: 71162
• CAS Number: 10236-47-2
• M. F.: C27H32O14
• M. W.: 580.53458
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: 7-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
• IUPAC Traditional name: 7-{[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-1-benzopyran-4-one
• Synonyms: Naringenine-7-rhamnosidoglucoside; 4′,5,7-Trihydroxyflavanone 7-rhamnoglucoside

DATABASE IDS

• CAS Number: 10236-47-2
• MDL Number: MFCD00148888
• Beilstein Number: 102012
• PubChem SID: 24886149
• EC Number: 233-566-4

PROPERTIES

• Empirical Formula (Hill Notation): C27H32O14
• Purity: ≥95% (HPLC)
• Optical Rotation: [α]20/D -80±10°, c = 1% in ethanol
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: QN6340000
• Safety Statements: 26
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Naringin, a flavanoid in grapefruit and other citrus fruits, potently inhibits intestinal organic anion-transporting polypeptide 1A2 (OATP1A2). Grapefruit juice thereby reduces bioavailability of many pharmacological agents taken at the same time.1

Description (简体中文)

Biochem/physiol Actions
Naringin, a flavanoid in grapefruit and other citrus fruits, potently inhibits intestinal organic anion-transporting polypeptide 1A2 (OATP1A2). Grapefruit juice thereby reduces bioavailability of many pharmacological agents taken at the same time.1