1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

• Catalog No.: 42490
• CAS Number: 4004-05-1
• M. F.: C41H78NO8P
• M. W.: 744.033681
• Purity: ≥99.0% (10 mg phospholipid per ml CHCl3, TLC)

SYNONYMS

• Title: 1,2-二油酰-sn-甘油-3-磷酸乙醇胺
• IUPAC name: (2-aminoethoxy)[(2R)-2,3-bis(octadec-9-enoyloxy)propoxy]phosphinic acid
• IUPAC Traditional name: 2-aminoethoxy(2R)-2,3-bis(octadec-9-enoyloxy)propoxyphosphinic acid
• Synonyms: 3-sn-Phosphatidylethanolamine, 1,2-dideoyl; (9Z)-9-Octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester; DOPE; Dioleoyl phosphatidylethanolamine; 1,2-Di(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; L-β,γ-Dioleoyl-α-cephalin; PE(18:1(9Z)/18:1(9Z))

DATABASE IDS

• Beilstein Number: 1718431
• CAS Number: 4004-05-1
• MDL Number: MFCD00057986
• PubChem SID: 24866597
• EC Number: 200-663-8

PROPERTIES

• Empirical Formula (Hill Notation): C41H78NO8P
• Purity: ≥99.0% (10 mg phospholipid per ml CHCl3, TLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H351-H373
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US)
• GHS Precautionary statements: P281
• RID/ADR: UN 1888 6.1/PG 3
• Risk Statements: 22-38-40-48/20/22
• Safety Statements: 36/37
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 1888
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (简体中文)

Application
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents 1.

Description (English)

Application
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) forms heterogenous liposomes with N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methylsulfate (DOTAP), which are used as delivery vehicles for therapeutic agents 1.