BICINE

• Catalog No.: 14871
• CAS Number: 150-25-4
• M. F.: C6H13NO4
• M. W.: 163.17172
• Purity: ≥99.5% (T)

SYNONYMS

• IUPAC name: 2-[bis(2-hydroxyethyl)amino]acetic acid
• IUPAC Traditional name: bicine
• Synonyms: N,N-Bis(2-hydroxyethyl)glycine; N,N-双(2-羟乙基)甘氨酸

DATABASE IDS

• MDL Number: MFCD00004295
• CAS Number: 150-25-4
• PubChem SID: 24848916
• EC Number: 205-755-1
• Beilstein Number: 1769362

PROPERTIES

• Antion Traces: chloride (Cl-): ≤50 mg/kg
• Antion Traces: sulfate (SO42-): ≤50 mg/kg
• Cation Traces: Al: ≤5 mg/kg
• Cation Traces: As: ≤0.1 mg/kg
• Cation Traces: Ba: ≤5 mg/kg
• Cation Traces: Bi: ≤5 mg/kg
• Cation Traces: Ca: ≤20 mg/kg
• Cation Traces: Cd: ≤5 mg/kg
• Cation Traces: Co: ≤5 mg/kg
• Cation Traces: Cr: ≤5 mg/kg
• Cation Traces: Cu: ≤5 mg/kg
• Cation Traces: Fe: ≤5 mg/kg
• Cation Traces: K: ≤50 mg/kg
• Cation Traces: Li: ≤5 mg/kg
• Cation Traces: Mg: ≤5 mg/kg
• Cation Traces: Mn: ≤5 mg/kg
• Cation Traces: Mo: ≤5 mg/kg
• Cation Traces: Na: ≤50 mg/kg
• Cation Traces: Ni: ≤5 mg/kg
• Cation Traces: Pb: ≤5 mg/kg
• Cation Traces: Sr: ≤5 mg/kg
• Cation Traces: Zn: ≤5 mg/kg
• Empirical Formula (Hill Notation): C6H13NO4
• Ignition Residue: ≤0.1%
• Impurities: insoluble matter, passes filter test
• λ: 1 M in H2O
• Loss on Drying: ≤0.1% loss on drying, 20 °C (HV)
• Product Line: BioUltra
• Purity: ≥99.5% (T)
• Useful pH Range: 7.6 - 9.0
• Absorption Wavelength: λ: 260 nm Amax: 0.070
• Absorption Wavelength: λ: 280 nm Amax: 0.040
• pKa: 8.3 (25°C)
• pH: 4.0-5.5 (25 °C, 1 M in H2O)
• Solubility: H2O: soluble1 M at 20 °C, clear, colorless
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Application
Recommended buffer for low temperature biochemical work.1 Used in the preparation of stable substrate solution for serum guanase determination.2 Spacer in plasma protein fractionation with Sephadex by isotachophoresis.3
BICINE can be used to study biological buffers and zwitterionic compounds. N,N-Bis(2-hydroxyethyl)glycine has been used in a study that characterized refined crystal structures of human Ca2+/Zn2+-binding S100A3 protein. N,N-Bis(2-hydroxyethyl)glycine has also been used in a study to inform F1 antigen assembly.

Description (简体中文)

Application
低温生化作业的推荐缓冲液。1用于制备测定血清鸟嘌呤酶的稳定底物溶液。2采用交联葡聚糖通过等速电泳对血浆蛋白进行分级分离中的间隔臂。3
BICINE can be used to study biological buffers and zwitterionic compounds. N,N-Bis(2-hydroxyethyl)glycine has been used in a study that characterized refined crystal structures of human Ca2+/Zn2+-binding S100A3 protein. N,N-Bis(2-hydroxyethyl)glycine has also been used in a study to inform F1 antigen assembly.