Amygdalin

• Catalog No.: 10050
• CAS Number: 29883-15-6
• M. F.: C20H27NO11
• M. W.: 457.42848
• Purity: ≥97.0% (HPLC)

SYNONYMS

• Title: 扁桃苷
• IUPAC name: 2-phenyl-2-{[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}acetonitrile
• IUPAC Traditional name: amygdalin
• Synonyms: D-Mandelonitrile 6-O-β-D-glucosido-β-D-glucoside; Laetrile; D-Mandelonitrile-β-gentiobioside; D-扁桃腈6-O-β-D-葡糖基-β-D-葡萄糖苷; D-扁桃腈-β-龙胆二糖苷; 苦杏仁苷

DATABASE IDS

• PubChem SID: 24846528
• MDL Number: MFCD00006598
• Beilstein Number: 66856
• EC Number: 249-925-3
• CAS Number: 29883-15-6

PROPERTIES

• Antion Traces: chloride (Cl-): ≤50 mg/kg
• Antion Traces: sulfate (SO42-): ≤300 mg/kg
• Cation Traces: Ca: ≤30 mg/kg
• Cation Traces: Cd: ≤5 mg/kg
• Cation Traces: Co: ≤5 mg/kg
• Cation Traces: Cr: ≤5 mg/kg
• Cation Traces: Cu: ≤5 mg/kg
• Cation Traces: Fe: ≤5 mg/kg
• Cation Traces: K: ≤300 mg/kg
• Cation Traces: Mg: ≤5 mg/kg
• Cation Traces: Mn: ≤5 mg/kg
• Cation Traces: Na: ≤50 mg/kg
• Cation Traces: Ni: ≤5 mg/kg
• Cation Traces: Pb: ≤5 mg/kg
• Cation Traces: Zn: ≤5 mg/kg
• Empirical Formula (Hill Notation): C20H27NO11
• Loss on Drying: ≤5% loss on drying, 110 °C
• Product Line: BioXtra
• Purity: ≥97.0% (HPLC)
• Melting Point: 210-215 °C
• Optical Rotation: [α]20/D -39±2°, c = 2% in H2O
• Solubility: H2O: soluble0.1 g/mL, clear to very faintly turbid, colorless (hot)
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• Risk Statements: 22
• RTECS: OO8450000
• Safety Statements: 26-36/37/39-45
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Cyanogenic glycoside that is a component of bitter almonds and apricot pits. There is no scientific evidence that amygdalin itself is an effective anti-cancer agent. Recent studies using β-glucoside linked to a tumor-associated monoclonal antibody to release cyanide at the tumor cell has shown significant cytotoxicity.
Other Notes
Review: Cyanogenic glycosides1
Application
Amygdalin, a cyanide containing glycoside, may be used as a substrate to identify, differentiate and characterize enzymes such as maltase(s), emulsin(s) and β-glucosidase(s).

Description (简体中文)

Biochem/physiol Actions
Cyanogenic glycoside that is a component of bitter almonds and apricot pits. There is no scientific evidence that amygdalin itself is an effective anti-cancer agent. Recent studies using β-glucoside linked to a tumor-associated monoclonal antibody to release cyanide at the tumor cell has shown significant cytotoxicity.
Other Notes
Review: Cyanogenic glycosides1
Application
Amygdalin, a cyanide containing glycoside, may be used as a substrate to identify, differentiate and characterize enzymes such as maltase(s), emulsin(s) and β-glucosidase(s).