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Guanidine thiocyanate_Molecular_structure_CAS_593-84-0)
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Guanidine thiocyanate

Catalog No. 50980 Name Sigma Aldrich
CAS Number 593-84-0 Website http://www.sigmaaldrich.com
M. F. C2H6N4S Telephone 1-800-521-8956
M. W. 118.16084 Fax
Purity ≥99.0% (AT) Email
Storage Chembase ID: 127626

SYNONYMS

Title
异硫氰酸胍
IUPAC name
guanidine; sulfanylformonitrile
IUPAC Traditional name
guanidine; thiocyanate ion
Synonyms
Guanidinium thiocyanate
硫氰酸亚脲
Guanidinium rhodanide
硫氰酸胍

DATABASE IDS

Beilstein Number 3563461
EC Number 209-812-1
PubChem SID 24873460
MDL Number MFCD00013027
CAS Number 593-84-0

PROPERTIES

Linear Formula NH2C(=NH)NH2 · HSCN
Loss on Drying ≤0.1% loss on drying, 20 °C (HV)
Product Line BioUltra
Purity ≥99.0% (AT)
Cation Traces Mn: ≤5 mg/kg
Cation Traces Mo: ≤5 mg/kg
Cation Traces Na: ≤5000 mg/kg
Cation Traces Ni: ≤5 mg/kg
Cation Traces Pb: ≤5 mg/kg
Cation Traces Sr: ≤5 mg/kg
Cation Traces Zn: ≤5 mg/kg
Grade for molecular biology
Ignition Residue ≤0.5% (as SO4)
Impurities DNases, none detected
Impurities RNases, none detected
Impurities insoluble matter, passes filter test
Impurities phosphatases, none detected
Impurities proteases, none detected
abs. absorption6M/280 nm, H2O cut-off
Antion Traces chloride (Cl-): ≤5000 mg/kg
Antion Traces sulfate (SO42-): ≤50 mg/kg
Cation Traces Al: ≤5 mg/kg
Cation Traces As: ≤0.1 mg/kg
Cation Traces Ba: ≤5 mg/kg
Cation Traces Bi: ≤5 mg/kg
Cation Traces Ca: ≤10 mg/kg
Cation Traces Cd: ≤5 mg/kg
Cation Traces Co: ≤5 mg/kg
Cation Traces Cr: ≤5 mg/kg
Cation Traces Cu: ≤5 mg/kg
Cation Traces Fe: ≤5 mg/kg
Cation Traces K: ≤50 mg/kg
Cation Traces Li: ≤5 mg/kg
Cation Traces Mg: ≤5 mg/kg
Melting Point 117-120 °C
Melting Point 120-122 °C(lit.)
pH 4.5-7.0 (25 °C, 6 M in H2O)
Solubility H2O: soluble6 M at 20 °C, clear, colorless
GHS Pictograms GHS05
GHS Pictograms GHS07
GHS Signal Word Danger
GHS Hazard statements H302 + H312 + H332-H314-H412
European Hazard Symbols Corrosive Corrosive (C)
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P273-P280-P305 + P351 + P338-P310
Risk Statements 20/21/22-32-34-52/53
RTECS XL1225000
Safety Statements 13-26-36/37/39-45-61
Supplemental Hazard Statements Contact with acids liberates very toxic gas.
German water hazard class 2

DETAILS

Description (English)
Application
Chaotropic agent and strong denaturant; solubilizes cells.
Other Notes
Isolation of RNA1,2; A new guanidine thiocyanate procedure for the isolation of full-length RNA templates for reverse transcription from tissues rich in RNase and proteoglycans3
Description (简体中文)
Application
离液剂和强效变性剂;溶解细胞。
Other Notes
Isolation of RNA1,2; A new guanidine thiocyanate procedure for the isolation of full-length RNA templates for reverse transcription from tissues rich in RNase and proteoglycans3

REFERENCES