L-C-Propargylglycine

• Catalog No.: 81838
• CAS Number: 23235-01-0
• M. F.: C4H5NO2
• M. W.: 99.088
• Purity: ≥99.0% (TLC)

SYNONYMS

• IUPAC name: (2S)-2-aminobut-3-ynoic acid
• IUPAC Traditional name: L-propargylglycine
• Synonyms: L-Propargylglycine; (S)-2-Amino-4-pentynoic acid

DATABASE IDS

• Beilstein Number: 2347861
• CAS Number: 23235-01-0
• MDL Number: MFCD00077855
• PubChem SID: 24887908

PROPERTIES

• Empirical Formula (Hill Notation): C5H7NO2
• Purity: ≥99.0% (TLC)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Reagent for the irreversible inactivation of γ-cystathionase1,2; affinity labeling reagent for γ-cystathionase and other enzymes3; peptides containing this amino acid can be tritiated to high specific radioactivity4
Biochem/physiol Actions
L-C-Propargylglycine, a specific inhibitor of H(2)S synthase of cystathionine-γ-lyase (CSE), may be used to study the role of H2S in regulation of biological processes.
L-propargylglycine (PAG), an inhibitor of cystathionine γ-lyase (CSE), is useful in studies of hydrogen sulphide synthesis and bioactivity.

Description (简体中文)

Application
Reagent for the irreversible inactivation of γ-cystathionase1,2; affinity labeling reagent for γ-cystathionase and other enzymes3; peptides containing this amino acid can be tritiated to high specific radioactivity4
Biochem/physiol Actions
L-propargylglycine (PAG), an inhibitor of cystathionine γ-lyase (CSE), is useful in studies of hydrogen sulphide synthesis and bioactivity.