Phorbol 12-myristate 13-acetate

• Catalog No.: 79346
• CAS Number: 16561-29-8
• M. F.: C36H56O8
• M. W.: 616.82504
• Purity: ≥98.0% (TLC)

SYNONYMS

• IUPAC name: (1S,2S,6R,10S,11R,13S,14R,15R)-13-(acetyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^2,^6.0^1^1,^1^3]pentadeca-3,8-dien-14-yl tetradecanoate
• IUPAC Traditional name: phorbol ester
• Synonyms: 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate; 12-O-Tetradecanoylphorbol 13-acetate; PMA; TPA

DATABASE IDS

• MDL Number: MFCD00036736
• Beilstein Number: 2407201
• PubChem SID: 24887446
• CAS Number: 16561-29-8

PROPERTIES

• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 38
• RTECS: QH4377000
• Safety Statements: 36/37
• Storage Temperature: -20°C
• German water hazard class: 3
• GHS Signal Word: Warning
• GHS Hazard statements: H315
• European Hazard Symbols: Irritant (Xi)
• Empirical Formula (Hill Notation): C36H56O8
• Purity: ≥98.0% (TLC)
• Quality: synthetic
• Solubility: chloroform: soluble10 mg/mL, clear, colorless to light yellow

DETAILS

Description (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
Potent tumor promoter; activates protein kinase C in vivo and in vitro.
Other Notes
Activates protein kinase C in vivo and in vitro at nanomolar concentrations1; Highly potent tumor promotor and mitogen: active principle of croton oil. Review2

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
Potent tumor promoter; activates protein kinase C in vivo and in vitro.
Other Notes
Activates protein kinase C in vivo and in vitro at nanomolar concentrations1; Highly potent tumor promotor and mitogen: active principle of croton oil. Review2