Coumestrol

• Catalog No.: 27883
• CAS Number: 479-13-0
• M. F.: C15H8O5
• M. W.: 268.22102
• Purity: ≥97.5% (HPLC)

SYNONYMS

• IUPAC name: 5,14-dihydroxy-8,17-dioxatetracyclo[8.7.0.0^2,^7.0^1^1,^1^6]heptadeca-1(10),2,4,6,11(16),12,14-heptaen-9-one
• IUPAC Traditional name: coumestrol
• Synonyms: 7,12-Dihydroxycoumestan

DATABASE IDS

• CAS Number: 479-13-0
• MDL Number: MFCD00016885
• Beilstein Number: 266702
• PubChem SID: 24856835
• EC Number: 207-525-6

PROPERTIES

• Empirical Formula (Hill Notation): C15H8O5
• Product Line: BioReagent
• Purity: ≥97.5% (HPLC)
• Suitability: suitable for fluorescence
• Gene Information: human ... ESR1(2099), ESR2(2100)mouse ... Esr1(13982)rat ... Ar(24208)
• Fluorescence: λex 377 nm; λem 437 nm in 0.1 M Tris pH 8.0
• Melting Point: ≥350 °C(lit.)
• Solubility: DMSO: soluble
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H315-H319-H335
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 22-36/37/38
• RTECS: DF8077000
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.1

Description (简体中文)

Biochem/physiol Actions
Coumestrol has anti-estrogenic actions in the brain and pituitary, mediated through estrogen receptor-α.1