Choline chloride

• Catalog No.: 26978
• CAS Number: 67-48-1
• M. F.: C5H14ClNO
• M. W.: 139.62376
• Purity: ≥99.0% (AT)

SYNONYMS

• Title: 氯化胆碱
• IUPAC name: (2-hydroxyethyl)trimethylazanium chloride
• IUPAC Traditional name: choline chloride
• Synonyms: (2-Hydroxyethyl)trimethylammonium chloride; (2-羟乙基)三甲基氯化铵

DATABASE IDS

• CAS Number: 67-48-1
• Beilstein Number: 3563126
• PubChem SID: 24856348
• MDL Number: MFCD00011721
• EC Number: 200-655-4

PROPERTIES

• Antion Traces: sulfate (SO42-): ≤50 mg/kg
• Cation Traces: Al: ≤5 mg/kg
• Cation Traces: Ba: ≤5 mg/kg
• Cation Traces: Bi: ≤5 mg/kg
• Cation Traces: Ca: ≤10 mg/kg
• Cation Traces: Cd: ≤5 mg/kg
• Cation Traces: Co: ≤5 mg/kg
• Cation Traces: Cr: ≤5 mg/kg
• Cation Traces: Cu: ≤5 mg/kg
• Cation Traces: Fe: ≤5 mg/kg
• Cation Traces: K: ≤50 mg/kg
• Cation Traces: Li: ≤5 mg/kg
• Cation Traces: Mg: ≤5 mg/kg
• Cation Traces: Mn: ≤5 mg/kg
• Cation Traces: Mo: ≤5 mg/kg
• Cation Traces: Na: ≤50 mg/kg
• Cation Traces: Ni: ≤5 mg/kg
• Cation Traces: Pb: ≤5 mg/kg
• Cation Traces: Sr: ≤5 mg/kg
• Cation Traces: Zn: ≤5 mg/kg
• Impurities: insoluble matter, passes filter test
• λ: 1 M in H2O
• Linear Formula: (CH3)3N(Cl)CH2CH2OH
• Product Line: BioUltra
• Purity: ≥99.0% (AT)
• Absorption Wavelength: λ: 260 nm Amax: 0.015
• Absorption Wavelength: λ: 280 nm Amax: 0.010
• Melting Point: 302-305 °C (dec.)(lit.)
• pH: 5.0-7.5 (25 °C, 1 M in H2O)
• Solubility: H2O: soluble1 M, clear, colorless
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: KH2975000
• Safety Statements: 26-36
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes 1.
Other Notes
Restores cholinergic, biochemical and pharmacological activities in striata of decorticated rats2
Sales restrictions may apply
Substrates
Choline acetyltransferase substrate

Description (简体中文)

Biochem/physiol Actions
Choline is an essential nutrient, commonly grouped with the B complex vitamins, that plays key roles in many biological processes.
The enzymatic activities of butyrylcholinesterase (BChE) and paraoxonase 1 (PON1), two serum enzymes synthesized by the liver and related with inflammation, were decreased in a sepsis animal model injected with LPS. Choline chloride administered intravenously at 20 mg/kg body weight prevents the LPS-mediated decreases in the activities of these two enzymes 1.
Other Notes
Restores cholinergic, biochemical and pharmacological activities in striata of decorticated rats2
Sales restrictions may apply
Substrates
胆碱乙酰基转移酶底物