Uricase from Bacillus fastidiosus

• Catalog No.: 94310
• CAS Number: 9002-12-4
• M. F.: C18H26N5O14P
• M. W.: 567.397901

SYNONYMS

• IUPAC name: {[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy})phosphinic acid amine
• IUPAC Traditional name: [5-(2,4-dioxo-3H-pyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy[5-(2,4-dioxo-3H-pyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyphosphinic acid amine

DATABASE IDS

• EC Number: 232-655-5
• CAS Number: 9002-12-4
• PubChem SID: 24889980
• Enzyme Commission Number: 1.7.3.3 ( BRENDA
• MDL Number: MFCD00082126
• Enzyme Commission Number: IUBMB )

PROPERTIES

• Quality: lyophilized
• Quality Level: PREMIUM
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: YU7100000
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
For the determination of uric acid in biological fluids2; In the spectrophotometric determination of purines and purine nucleosides3.
Unit Definition
1 U corresponds to the amount of enzyme which oxidizes 1 μmole uric acid at pH 9.1 and 37 °C.
Application
Uricase may be used for the determination of uric acid in biological fluids. It may be helpful in the spectrophotometric determination of purines and purine nucleosides.
Biochem/physiol Actions
Uricase catalyzes the oxidation of uric acid to 5-hydroxyisourate, which subsequently forms (S)-allantoin. It is involved in purine metabolism, urate degradation and (S)-allantoin formation 1.

Description (简体中文)

Other Notes
For the determination of uric acid in biological fluids1; In the spectrophotometric determination of purines and purine nucleosides2.
Unit Definition
1 U corresponds to the amount of enzyme which oxidizes 1 μmole uric acid at pH 9.1 and 37 °C.