D-Mannitol

• Catalog No.: 63559
• CAS Number: 69-65-8
• M. F.: C6H14O6
• M. W.: 182.17176
• Purity: ≥99.0% (sum of enantiomers, HPLC)

SYNONYMS

• Title: D-甘露糖醇
• IUPAC name: (2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexol
• IUPAC Traditional name: mannitol
• Synonyms: 甘露醇; Mannite

DATABASE IDS

• PubChem SID: 24882727
• CAS Number: 69-65-8
• Beilstein Number: 1721898
• EC Number: 200-711-8
• MDL Number: MFCD00064287

PROPERTIES

• Antion Traces: chloride (Cl-): ≤50 mg/kg
• Antion Traces: sulfate (SO42-): ≤50 mg/kg
• Cation Traces: Al: ≤5 mg/kg
• Cation Traces: As: ≤0.1 mg/kg
• Cation Traces: Ba: ≤5 mg/kg
• Cation Traces: Bi: ≤5 mg/kg
• Cation Traces: Ca: ≤10 mg/kg
• Cation Traces: Cd: ≤5 mg/kg
• Cation Traces: Co: ≤5 mg/kg
• Cation Traces: Cr: ≤5 mg/kg
• Cation Traces: Cu: ≤5 mg/kg
• Cation Traces: Fe: ≤5 mg/kg
• Cation Traces: K: ≤50 mg/kg
• Cation Traces: Li: ≤5 mg/kg
• Cation Traces: Mg: ≤5 mg/kg
• Cation Traces: Mn: ≤5 mg/kg
• Cation Traces: Mo: ≤5 mg/kg
• Cation Traces: Na: ≤50 mg/kg
• Cation Traces: Ni: ≤1 mg/kg
• Cation Traces: Pb: ≤1 mg/kg
• Cation Traces: Sr: ≤5 mg/kg
• Cation Traces: Zn: ≤5 mg/kg
• Empirical Formula (Hill Notation): C6H14O6
• Ignition Residue: ≤0.01% (as SO4)
• Impurities: insoluble matter, passes filter test
• Impurities: reducing sugars, complies
• Impurities: ≤0.0072% free acid (as CH3COOH)
• λ: 1 M in H2O
• Loss on Drying: ≤0.05% loss on drying, 20 °C (HV)
• Product Line: BioUltra
• Purity: ≥99.0% (sum of enantiomers, HPLC)
• Absorption Wavelength: λ: 260 nm Amax: 0.04
• Absorption Wavelength: λ: 280 nm Amax: 0.04
• Melting Point: 166-168 °C
• Melting Point: 167-170 °C(lit.)
• Optical Rotation: [α]20/D +24.0±1° in borax solution acc. to Ph Eur
• pH: 5.0-6.5 (25 °C, 1 M in H2O)
• Solubility: H2O: soluble1 M at 20 °C, clear, colorless
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: OP2060000
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
A sugar alcohol sweet tastant. Used in sweetness inhibition studies.
Other Notes
Used in discontinuous gradient centrifugation for purification of plant protoplasts1. Plasmolyticum that reversibly inhibits phenylalanine ammonia-lyase activity of protoplasts at concentrations exceeding 50 mM2. Component of the liquid stationary phase in the GLC separation of nitroxylene and xylenol isomers3.
Application
D-Mannitol is used as an osmolyte and transport facilitator in a variety of biological in vivo and in vitro applications, such as improvement of blood-brain barrier transport and hyperosmolar therapy. D-Mannitol is used as a substrate to identify, differentiate and characterized enzymes such as mannitol dehydrogenase(s). D-Mannitol is used in identify mannitol metabolizing bacteria.

Description (简体中文)

Biochem/physiol Actions
糖醇甜促味剂。用于甜味抑制研究。
Other Notes
Used in discontinuous gradient centrifugation for purification of plant protoplasts1. Plasmolyticum that reversibly inhibits phenylalanine ammonia-lyase activity of protoplasts at concentrations exceeding 50 mM2. Component of the liquid stationary phase in the GLC separation of nitroxylene and xylenol isomers3.
Application
D-Mannitol is used as an osmolyte and transport facilitator in a variety of biological in vivo and in vitro applications, such as improvement of blood-brain barrier transport and hyperosmolar therapy. D-Mannitol is used as a substrate to identify, differentiate and characterized enzymes such as mannitol dehydrogenase(s). D-Mannitol is used in identify mannitol metabolizing bacteria.