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Amentoflavone

Catalog No. 40584 Name Sigma Aldrich
CAS Number 1617-53-4 Website http://www.sigmaaldrich.com
M. F. C30H18O10 Telephone 1-800-521-8956
M. W. 538.45792 Fax
Purity ≥99.0% (HPLC) Email
Storage Chembase ID: 125787

SYNONYMS

IUPAC name
8-[5-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
IUPAC Traditional name
amentoflavone
Synonyms
Didemethyl-ginkgetin

DATABASE IDS

MDL Number MFCD00017470
CAS Number 1617-53-4
PubChem SID 24865336
Beilstein Number 380244

PROPERTIES

Empirical Formula (Hill Notation) C30H18O10
Purity ≥99.0% (HPLC)
Gene Information human ... GABRA1(2554)
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs.1 Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site.
Description (简体中文)
Biochem/physiol Actions
Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs.1 Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site.

REFERENCES