Dansylcadaverine

• Catalog No.: 30432
• CAS Number: 10121-91-2
• M. F.: C17H25N3O2S
• M. W.: 335.4643
• Purity: ≥99.0% (HPLC)

SYNONYMS

• IUPAC name: N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide
• IUPAC Traditional name: N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide
• Synonyms: N-(5-Amino-pentyl)-5-di-methyl-amino-naphtha-lene-1-sulfon-amide; N-(Dimethyl-amino-naphtha-lene-sulfonyl)-1,5-pentane-diamine; Monodansyl cadaverine

DATABASE IDS

• Beilstein Number: 2951070
• CAS Number: 10121-91-2
• MDL Number: MFCD00042704
• PubChem SID: 24858361
• EC Number: 233-326-9

PROPERTIES

• Empirical Formula (Hill Notation): C17H25N3O2S
• Product Line: BioReagent
• Purity: ≥99.0% (HPLC)
• Suitability: suitable for fluorescence
• Fluorescence: λex 335 nm; λem 518 nm in methanol
• Fluorescence: λex 338 nm; λem 500 nm (Reaction product)
• Melting Point: 137-140 °C
• Solubility: Do you have solubility information on this product that you would like to share?
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Frequently Asked Questions
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Application
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Biochem/physiol Actions
Inhibitor of the fibrin-stabilizing fator;1 Inhibitor of epidermal growth factor (EGF) internalization;2 Fluorescent substrate for the assay of transamidating enzymes.3,4
The autofluorescent dye dansylcadaverine, or monodansylcadaverine (MDC), is commonly used to monitor autophagy. MDC preferentially accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids.
Other Notes
Solubility of dansylcadaverine is tested in methanol (10 mg/mL). It has also been reported that dansylcadaverine is soluble in DMSO and acetic acid.

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Do you have application information on this product that you would like to share?
Biochem/physiol Actions
Inhibitor of the fibrin-stabilizing fator;1 Inhibitor of epidermal growth factor (EGF) internalization;2 Fluorescent substrate for the assay of transamidating enzymes.3,4
The autofluorescent dye dansylcadaverine, or monodansylcadaverine (MDC), is commonly used to monitor autophagy. MDC preferentially accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids.
Other Notes
Solubility of dansylcadaverine is tested in methanol (10 mg/mL). It has also been reported that dansylcadaverine is soluble in DMSO and acetic acid.