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1,4-Dithioerythritol_Molecular_structure_CAS_6892-68-8)
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1,4-Dithioerythritol

Catalog No. 43794 Name Sigma Aldrich
CAS Number 6892-68-8 Website http://www.sigmaaldrich.com
M. F. C4H10O2S2 Telephone 1-800-521-8956
M. W. 154.251 Fax
Purity ≥99.0% (RT) Email
Storage Chembase ID: 127163

SYNONYMS

Title
1,4-二硫代赤藓醇
IUPAC name
(2R,3S)-1,4-disulfanylbutane-2,3-diol
IUPAC Traditional name
dithioerythritol
Synonyms
Cleland’s reagent
DTE
克莱兰氏试剂
二硫代赤丁四醇
Erythro-2,3-dihydroxy-1,4-butanedithiol
Erythro-1,4-dimercapto-2,3-butanediol
赤式1,4-二巯基-2,3-丁二醇

DATABASE IDS

CAS Number 6892-68-8
PubChem SID 24867409
MDL Number MFCD00063750
EC Number 229-998-8
Beilstein Number 1719756

PROPERTIES

Antion Traces sulfate (SO42-): ≤50 mg/kg
Cation Traces Al: ≤5 mg/kg
Cation Traces As: ≤0.5 mg/kg
Cation Traces Ba: ≤5 mg/kg
Cation Traces Bi: ≤5 mg/kg
Cation Traces Ca: ≤50 mg/kg
Cation Traces Cd: ≤5 mg/kg
Cation Traces Co: ≤5 mg/kg
Cation Traces Cr: ≤5 mg/kg
Cation Traces Cu: ≤5 mg/kg
Cation Traces Fe: ≤5 mg/kg
Cation Traces K: ≤50 mg/kg
Cation Traces Li: ≤5 mg/kg
Cation Traces Mg: ≤5 mg/kg
Cation Traces Mn: ≤5 mg/kg
Cation Traces Mo: ≤5 mg/kg
Cation Traces Na: ≤50 mg/kg
Cation Traces Ni: ≤5 mg/kg
Cation Traces Pb: ≤5 mg/kg
Cation Traces Sr: ≤5 mg/kg
Cation Traces Zn: ≤5 mg/kg
Impurities insoluble matter, passes filter test
Impurities ≤0.5% 4,5-dihydroxy-1,2-dithiane
λ 0.1 M in H2O
Linear Formula HSCH2CH(OH)CH(OH)CH2SH
Product Line BioUltra
Purity ≥99.0% (RT)
Absorption Wavelength λ: 260 nm Amax: 0.400
Absorption Wavelength λ: 280 nm Amax: 0.050
Melting Point 82-84 °C(lit.)
Melting Point 82-85 °C
pH 4.0-6.0 (25 °C, 0.1 M in H2O)
Solubility H2O: soluble0.1 M at 20 °C, clear, colorless
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS KF2410000
Safety Statements 26-36
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Application
Reagent for maintaining -SH groups in the reduced state; quantitatively reduces disulfides.
Other Notes
Cleavage of disulfide bonds in proteins;1,2 Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis.3
Description (简体中文)
Application
用于将 -SH 基保持在还原态的试剂;定量还原二硫化物。
Other Notes
Cleavage of disulfide bonds in proteins;1,2 Prevents oxidation of sulfhydryl-containing proteins during SDS-polyacrylamide gel electrophoresis.3

REFERENCES