Levofloxacin

• Catalog No.: 28266
• CAS Number: 100986-85-4
• M. F.: C18H20FN3O4
• M. W.: 361.3675032
• Purity: ≥98.0% (HPLC)

SYNONYMS

• IUPAC name: (2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^5,^1^3]trideca-5(13),6,8,11-tetraene-11-carboxylic acid
• IUPAC Traditional name: levofloxacin
• Synonyms: (-)-Ofloxacin

DATABASE IDS

• CAS Number: 100986-85-4
• MDL Number: MFCD00865049
• PubChem SID: 24857060
• Beilstein Number: 7327015

PROPERTIES

• Empirical Formula (Hill Notation): C18H20FN3O4
• Purity: ≥98.0% (HPLC)
• Gene Information: human ... KCNH1(3756)
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H317-H334-H361d-H362
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P263-P280-P342 + P311
• Risk Statements: 63-22-42/43-64
• RTECS: UU8815550
• Safety Statements: 26-36/37/39
• German water hazard class: 3

DETAILS

Description (English)

Other Notes
Antibiotic against bacterial respiratory tract infections5,6
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 28266.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Application
Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic 1, antibiotic resistance 2 , and resistance prevention 3studies.
Biochem/physiol Actions
Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, 4 thereby inhibiting cell division.

Description (简体中文)

Other Notes
Antibiotic against bacterial respiratory tract infections5,6
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 28266.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Application
Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic 1, antibiotic resistance 2 , and resistance prevention 3studies.
Biochem/physiol Actions
Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, 4 thereby inhibiting cell division.