Sparfloxacin

• Catalog No.: 56968
• CAS Number: 110871-86-8
• M. F.: C19H22F2N4O3
• M. W.: 392.3997864
• Purity: ≥98.0% (HPLC)

SYNONYMS

• Title: 司帕沙星
• IUPAC name: 5-amino-1-cyclopropyl-7-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
• IUPAC Traditional name: sparfloxacin
• Synonyms: 5-氨基-1-环丙基-7-(顺式-3,5-二甲基-1-哌嗪基)-6,8-二氟-1,4-二氢-4-氧代-3-喹啉羧酸; 5-Amino-1-cyclohexyl-7-(cis-3,5-dimethylpiperazino)-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

DATABASE IDS

• MDL Number: MFCD00869619
• CAS Number: 110871-86-8
• Beilstein Number: 9170271
• PubChem SID: 24880518

PROPERTIES

• Empirical Formula (Hill Notation): C19H22F2N4O3
• Purity: ≥98.0% (HPLC)
• Gene Information: human ... KCNH1(3756), TOP2A(7153)
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• RTECS: VB1986500
• Safety Statements: 26-36
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. Used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation.
Other Notes
Antibacterial agents against respiratory tract infections2
Application
Sparfoxacin is a fluoroquinolone antibiotic used to study antimicrobial activity against mycobacteria and respiratory tract infections 1.

Description (简体中文)

Biochem/physiol Actions
Inhibits bacterial DNA gyrase (topoisomerase II) and/or topoisomerase IV. Used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent) DNA supercoiling, and chromosome fragmentation.
Other Notes
Antibacterial agents against respiratory tract infections2
Application
Sparfoxacin is a fluoroquinolone antibiotic used to study antimicrobial activity against mycobacteria and respiratory tract infections 1.