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1,8-Dihydroxy-3-methylanthraquinone_Molecular_structure_CAS_481-74-3)
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1,8-Dihydroxy-3-methylanthraquinone

Catalog No. 229075 Name Sigma Aldrich
CAS Number 481-74-3 Website http://www.sigmaaldrich.com
M. F. C15H10O4 Telephone 1-800-521-8956
M. W. 254.2375 Fax
Purity 98% Email
Storage Chembase ID: 73025

SYNONYMS

IUPAC name
1,8-dihydroxy-3-methyl-9,10-dihydroanthracene-9,10-dione
IUPAC Traditional name
turkey rhubarb
Synonyms
Chrysophanic acid

DATABASE IDS

EC Number 207-572-2
MDL Number MFCD00001208
CAS Number 481-74-3
PubChem SID 24853726
Beilstein Number 1252300

PROPERTIES

Empirical Formula (Hill Notation) C15H10O4
Purity 98%
Gene Information human ... ELA2(1991)
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P305 + P351 + P338
Risk Statements 36/38
RTECS CB6725000
Safety Statements 26
German water hazard class 3

DETAILS

Description (English)
Packaging
1 g in glass bottle
50 mg in glass bottle
Application
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Biochem/physiol Actions
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway 1. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus 2.
Description (简体中文)
包装
1 g in glass bottle
50 mg in glass bottle
Application
Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Biochem/physiol Actions
Anticancer activity for chrysophanic acid is via the EGFR/mTOR mediated signaling transduction pathway 1. Chrysophanic acid has two hydrophobic positions on the molecule (C-6 and the methyl group attached to C-3) which are responsible for the compound′s activity against poliovirus 2.

REFERENCES