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TCPOBOP

Catalog No. T1443 Name Sigma Aldrich
CAS Number 76150-91-9 Website http://www.sigmaaldrich.com
M. F. C16H8Cl4N2O2 Telephone 1-800-521-8956
M. W. 402.05892 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 155770

SYNONYMS

IUPAC name
3,5-dichloro-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}pyridine
IUPAC Traditional name
3,5-dichloro-2-{4-[(3,5-dichloropyridin-2-yl)oxy]phenoxy}pyridine
Synonyms
1,4-Bis-[2-(3,5-dichloropyridyloxy)]benzene
3,3′,5,5′-Tetrachloro-1,4-bis(pyridyloxy)benzene

DATABASE IDS

PubChem SID 24278723
MDL Number MFCD00057368
CAS Number 76150-91-9

PROPERTIES

Empirical Formula (Hill Notation) C16H8N2O2Cl4
Purity ≥98% (HPLC)
Gene Information human ... NR1I3(9970)
Apperance white solid
Solubility DMSO: >10 mg/mL
Solubility H2O: insoluble
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RTECS UT7145000
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. The most potent known member of the phenobarbital-like class of CYP-inducing agents.
Description (简体中文)
Biochem/physiol Actions
TCPOBOP enhances the nuclear receptor CAR transactivation of cytochrome P450 (CYP), as dose-dependent direct agonist of CAR. The most potent known member of the phenobarbital-like class of CYP-inducing agents.

REFERENCES