GW8510

• Catalog No.: G7791
• CAS Number: 222036-17-1
• M. F.: C21H15N5O3S2
• M. W.: 449.5055

SYNONYMS

• IUPAC name: 4-[({7-oxo-6H,7H,8H-[1,3]thiazolo[5,4-e]indol-8-ylidene}methyl)amino]-N-(pyridin-2-yl)benzene-1-sulfonamide
• IUPAC Traditional name: 4-[({7-oxo-6H-[1,3]thiazolo[5,4-e]indol-8-ylidene}methyl)amino]-N-(pyridin-2-yl)benzenesulfonamide
• Synonyms: 4-{[(7-Oxo-6,7-dihydro-8H-[1,3]thiazolo[5,4-e]indol-8-ylidene)methyl]amino}-N-(2-pyridyl)benzenesulfonamide

DATABASE IDS

• MDL Number: MFCD03452930
• PubChem SID: 24895323
• CAS Number: 222036-17-1

PROPERTIES

• Empirical Formula (Hill Notation): C21H15N5O3S2
• Gene Information: human ... CDC2(983), CDK2(1017)
• Apperance: solid
• Solubility: DMSO: soluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
GW8510 is an inhibitor of cyclin kinase 2 (CDK2). It prevents and/or reduces the side effects of chemotherapy (alopecia, plantar-palmar syndrome and mucositis).
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline

Description (简体中文)

Biochem/physiol Actions
GW8510 is an inhibitor of cyclin kinase 2 (CDK2). It prevents and/or reduces the side effects of chemotherapy (alopecia, plantar-palmar syndrome and mucositis).
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline