SCH-202676 hydrobromide

• Catalog No.: S4063
• M. F.: C15H14BrN3S
• M. W.: 348.26076
• Purity: 98%

SYNONYMS

• IUPAC name: N-methyl-2,3-diphenyl-2,5-dihydro-1,2,4-thiadiazol-5-imine hydrobromide
• IUPAC Traditional name: N-methyl-2,3-diphenyl-1,2,4-thiadiazol-5-imine hydrobromide
• Synonyms: N-(2,3-diphenyl-1,2,4-thiadiazol-5-(2H)-ylidene)methanamine hydrobromide

DATABASE IDS

• PubChem SID: 24278706
• MDL Number: MFCD06671539

PROPERTIES

• Empirical Formula (Hill Notation): C15H16BrN3S
• Purity: 98%
• Melting Point: 240.0-240.8 °C(lit.)
• Solubility: DMSO: soluble40 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Allosteric agonist and antagonist of G-protein coupled receptors (GPCRs).
General description
Shown to modulate radioligand binding to various GPCRs including the human μ-, δ-, and κ-opiod, α- and β-adrenergic, muscarinic M1 and M2, and dopaminergic D1 and D2 receptors. Modulation is G-protein independent and is both selective and reversible.

Description (简体中文)

Biochem/physiol Actions
Allosteric agonist and antagonist of G-protein coupled receptors (GPCRs).
General description
Shown to modulate radioligand binding to various GPCRs including the human μ-, δ-, and κ-opiod, α- and β-adrenergic, muscarinic M1 and M2, and dopaminergic D1 and D2 receptors. Modulation is G-protein independent and is both selective and reversible.