Pirfenidone

• Catalog No.: P2116
• CAS Number: 53179-13-8
• M. F.: C12H11NO
• M. W.: 185.22184
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: 5-methyl-1-phenyl-1,2-dihydropyridin-2-one
• IUPAC Traditional name: pirfenidone
• Synonyms: 5-Methyl-1-phenyl-2-(1H)-pyridone

DATABASE IDS

• PubChem SID: 24278625
• CAS Number: 53179-13-8
• MDL Number: MFCD00866047

PROPERTIES

• Empirical Formula (Hill Notation): C12H11NO
• Purity: ≥97% (HPLC)
• Solubility: H2O: >10 mg/mL at 60 °C (warming for 30 minutes)
• Solubility: DMSO: >20 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 22
• RTECS: UV1148200
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Pirfenidone inhibits collagen production and fibroblast proliferation. It has shown antifibrotic and anti-inflammatory properties in variety of animal models of pulmonary fibrosis, and in clinical trials.

Description (简体中文)

Biochem/physiol Actions
Pirfenidone inhibits collagen production and fibroblast proliferation. It has shown antifibrotic and anti-inflammatory properties in variety of animal models of pulmonary fibrosis, and in clinical trials.