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Dimethyl sulfoxide_Molecular_structure_CAS_67-68-5)
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Dimethyl sulfoxide

Catalog No. D2438 Name Sigma Aldrich
CAS Number 67-68-5 Website http://www.sigmaaldrich.com
M. F. C2H6OS Telephone 1-800-521-8956
M. W. 78.13344 Fax
Purity (USP XXIV) Email
Storage Chembase ID: 964

SYNONYMS

Title
二甲基亚砜
IUPAC name
methanesulfinylmethane
IUPAC Traditional name
dimethyl sulfoxide
Synonyms
DMSO
甲基亚砜
Methyl sulfoxide

DATABASE IDS

CAS Number 67-68-5
MDL Number MFCD00002089
EC Number 200-664-3
Beilstein Number 506008
PubChem SID 24893688

PROPERTIES

Grade Biotechnology Performance Certified
Linear Formula (CH3)2SO
Purity (USP XXIV)
Quality Level GMP
Sterility sterile-filtered
Suitability meets EP, USP testing specifications
Suitability suitable for hybridoma
Auto Ignition Point 573 °F
Boiling Point 189 °C(lit.)
Density 1.10 g/mL(lit.)
Flash Point 87 °C
Flash Point 188.6 °F
Melting Point 16-19 °C(lit.)
Refractive Index n20/D 1.479(lit.)
Vapor Density 2.7 (vs air)
Vapor Pressure 0.42 mmHg ( 20 °C)
Explode Limits 42 %, 63 °F
MSDS Link Download
Personal Protective Equipment Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
RTECS PV6210000
German water hazard class 1

DETAILS

Description (English)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
Human and animal cell lines grown in culture are generally stored frozen. Freezing protects the cell line from changes due to genetic drift and minimizes risk of contamination. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. Without the presence of a cryoprotective agent, freezing is lethal to most mammalian cells. Damage is caused by mechanical injury by ice crystals, concentration of electrolytes, pH changes, and denaturation of proteins. These lethal effects are minimized by adding a cryoprotective agent which lowers the freezing point and allows for a slower cooling rate. BPC-tested DMSO also meets the requirements of biotechnology and tissue engineering applications.
Caution
Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.
Features and Benefits
Ready-to-use sterile filtered product conveniently packaged septum screw-capped amber bottles. Meets USP and EP testing requirements
Description (简体中文)
Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Application
培养基中生长的人和动物细胞系通常采用冷冻保存。冷冻可以避免细胞系因遗传漂变而发生改变,并且可以最大限度降低被污染的风险。液氮与冷冻保护剂(诸如 DMSO)结合使用,是广泛采用的细胞保存方法。如果不使用冷冻保护剂,大多数哺乳动物细胞都会冷冻致死。冰晶将对细胞产生机械性损伤,此外电解液浓度、pH 值变化以及蛋白质变性,都将对细胞产生损害。冷冻保护剂将降低凝固点并保持更低的冷却速率,可最大限度减小这些致命影响。经生物技术性能认证 (BPC) 测试的 DMSO 还符合生物技术和组织工程应用的要求。
Caution
容易过度冷却,并在室温下缓慢融化固化的产品放在室温下可以再次液化,对其本身无影响。
Features and Benefits
产品经过消毒和过滤,包装在带隔垫的螺纹盖棕色瓶中,可立即使用。符合·USP 和·EP 测试要求

REFERENCES