Mitomycin C from Streptomyces caespitosus

• Catalog No.: M0440
• CAS Number: 50-07-7
• M. F.: C15H18N4O5
• M. W.: 334.32722
• Purity: ≥970 μg/mg (USP XXIV)

SYNONYMS

• Title: 丝裂霉素 C 来源于头状链霉菌
• IUPAC name: [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^2,^7.0^4,^6]trideca-1(9),11-dien-8-yl]methyl carbamate
• IUPAC Traditional name: mitamycin

DATABASE IDS

• CAS Number: 50-07-7
• Beilstein Number: 7231816
• PubChem SID: 24896554
• EC Number: 200-008-6
• MDL Number: MFCD00078109

PROPERTIES

• Empirical Formula (Hill Notation): C15H18N4O5
• Purity: ≥970 μg/mg (USP XXIV)
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H351
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P264-P281-P301 + P310
• RID/ADR: UN 3462 6.1/PG 2
• Risk Statements: 25-40
• RTECS: CN0700000
• Safety Statements: 28-36/37-45
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 3462
• Packing Group: 2
• German water hazard class: 3

DETAILS

Description (English)

Application
Used as a sequence specific (5′-CpG-3′) DNA crosslinking (alkylation) agent.
Biochem/physiol Actions
Inhibitor of DNA synthesis, nuclear division, and cancer cells. Antibacterial to gram positive, gram negative, acid-fast bacilli.
Other Notes
NaCl free
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Description (简体中文)

Application
Used as a sequence specific (5′-CpG-3′) DNA crosslinking (alkylation) agent.
Biochem/physiol Actions
DNA 合成、细胞核分裂和癌细胞的抑制剂。对革兰氏阳性菌、革兰氏阴性菌、抗酸杆菌有抗菌性。
Other Notes
无 NaCl
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information