Uricase from Candida sp.

• Catalog No.: U0880
• CAS Number: 9002-12-4
• M. F.: C18H26N5O14P
• M. W.: 567.397901

SYNONYMS

• IUPAC name: {[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy})phosphinic acid amine
• IUPAC Traditional name: [5-(2,4-dioxo-3H-pyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy[5-(2,4-dioxo-3H-pyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyphosphinic acid amine
• Synonyms: Urate: oxygen oxoreductase

DATABASE IDS

• PubChem SID: 24900619
• CAS Number: 9002-12-4
• Enzyme Commission Number: 1.7.3.3 ( BRENDA
• MDL Number: MFCD00082126
• Enzyme Commission Number: IUBMB )

PROPERTIES

• Mol. Weight: mol wt 35 kDa by SDS-PAGE
• Recombinant: expressed in E. coli
• Apperance: lyophilized powder
• Storage Temperature: -20°C
• German water hazard class: -

DETAILS

Description (English)

Biochem/physiol Actions
Suitable for the determination of uric acid in clinical analysis.
Unit Definition
One unit will oxidize 1.0 μmole of uric acid to allantoin per minute at pH 8.5 at 25 °C.
Physical form
Powder contains citrate.
General description
Mice deficient in uricase develop uric acid nephropathy and diabetes insipidus which can be mitigated with recombinant uricase treatment. 1

Description (简体中文)

Biochem/physiol Actions
Suitable for the determination of uric acid in clinical analysis.
Unit Definition
One unit will oxidize 1.0 μmole of uric acid to allantoin per minute at pH 8.5 at 25 °C.
Physical form
Powder contains citrate.